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November 10, 2008
Posted: 11:59 AM ET

by Miriam Falco
Managing Editor CNN Medical

A new study presented at a major heart conference over the weekend suggests that many of us who have good cholesterol numbers could help prevent heart disease by taking cholesterol-lowering drugs. Currently these drugs, known as statins, are prescribed only for people with existing heart problems and/or high bad cholesterol.

Could I be one of those candidates? Maybe I am, I don’t know. My cholesterol level is well below 200, which is what folks should aim for. But It’s been a couple of years since I last had my cholesterol checked, and I’m not sure how good my LDL, or “bad” cholesterol level is.

More important, people who participated in this study may have had optimal ‘bad” cholesterol levels, but they had high levels of “high-sensitivity C-reactive protein” or hsCRP, an indicator of inflammation in the body, which can contribute to the clogging of arteries. You may have had heard about CRP, but I for one have never had it tested.

Now, after folks read about this new research, they may be asking their doctors if they should get the test.

The men who particpated in this trial were 50 and older; the women were over age 60.

But as Dr. Elizabeth Nabel, director of the National Heart, Lung, Blood Institute, points out, adults at any age who are at “intermediate risk” for heart disease probably will want to talk to their doctor about having a ‘high-sensitivity C-reactive protein or ‘hsCRP” test.

How do you know if you are at intermediate risk?  Nabel suggests one way to determine your risk for heart disease is by checking the so-called “Framingham score,” which estimates the risk of developing coronary heart disease within 10 years based on risk factors including age, gender, cholesterol levels, blood pressure and if you smoke.

By using a simple risk calculator, which can be found here, anyone can calculate his or her risk for heart attack and coronary death.

If your score suggests you have a 10-20 percent risk of having a heart attack within the next 10 years, you are at “intermediate” risk.

Dr. Paul Ridker, from Brigham and Women’s Hospital in Boston, Massachusetts who is the lead researcher of this big study says there are two types of CRP tests – but only one tests for the high-sensitivity C-reactive protein. So patients who want to know if they should be taking statins even though they have good cholesterol levels, need to ask for an “hsCRP” blood test. The regular CRP test isn’t sensitive enough to detect the risky inflammation in people with normal to good cholesterol levels.

Do you think you might get your hsCRP tested?

Editor’s Note: Medical news is a popular but sensitive subject rooted in science. We receive many comments on this blog each day; not all are posted. Our hope is that much will be learned from the sharing of useful information and personal experiences based on the medical and health topics of the blog. We encourage you to focus your comments on those medical and health topics and we appreciate your input. Thank you for your participation.

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Filed under: Health • cholesterol • heart disease


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Denden Acompanado   November 13th, 2008 10:36 am ET

CRP is a good determinant to ascertain our risk for heart diseases. With this test the person is caution to change lifestyle early on even without experiencing the symptoms of heart diseases such as HPN or Angina. But, whether our CRP is tested or not we should develop a healthy lifestyle now since most of the patients we encounter in the area now are young adults related to heart diseases. An ounce of prevention is more important than a pound of cure.

Josephine Singer   November 14th, 2008 4:21 pm ET

I was taking a staten drug. (semistaten) My muscles started hurt very badly and I felt very weak. I have had open heart surgery and a pace maker put in slmost two years ago. The open heart surgery was to fixmy valve. If this staten hurt this badly would other statens do the same. I have talked to several people that takes semistaten and they all said they felt the way I felt, but not as badly as I did. I told My Dr. I went off of them but I have not seen him yet. Not until next year. My husband was taking the same type of drug and he felt the same and so is my son. My husband went off of them but my son has not yet. The V. A. Dr. does not want to take him off of yet. Niether of these two have heart problems.

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Get a behind-the-scenes look at the latest stories from CNN's chief medical correspondent, Dr. Sanjay Gupta, and the CNN Medical Unit producers. They'll share news and views on health and medical trends -- info that will help you take better care of yourself and the people you love.

Editor's Note

Medical news is a popular but sensitive subject rooted in science. We receive many comments on this blog each day; not all are posted. Our hope is that much will be learned from the sharing of useful information and personal experiences based on the medical and health topics of the blog. We encourage you to focus your comments on those medical and health topics and we appreciate your input. Thank you for your participation.

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